Vous essayez de contacter : Mlle EL KHATTABI Lamiae


ID-IRC : 2412050878

Chercheur Photo
EL KHATTABI Lamiae
Docteur (PHD)

Spécialité : Biochimie

Faculté des Sciences - Ben M’Sik de Casablanca
Faculté des Sciences - Ben M’Sik de Casablanca

Domaine de Maîtrise :
Biopathologie et Recherche Biomédicale

Domaine d’intérêt :

Biopathologie et Recherche Biomédicale**

Les publications :

Zouhdi, S., Elkhattabi, L., Mousstead, F., Kettani, A., & Saile, R. Structure-based virtual screening to identify hypocholesterolemic phytochemicals as potent inhibitors of squalene synthase, a potential target for hypercholesterolemia. Journal of Biomolecular Structure & Dynamics. Accepted April 24, 2024: Awaiting online production. Sifeddine, N., Elkhattabi, L., Ait El Cadi, C., et al. Insights from SNP analysis of the TYMP gene linking MNGIE. Bioinformation. 2024; 20(3): 261-270. DOI: 10.6026/973206300200261. PMID: 38712004; PMCID: PMC11069602. Lamiae Elkhattabi, Salwa Z., Fairouz M., Mohtadi K., Fougrach H., Badri W., Taki H., Kettani A., Talbi M., Saile R. Data insights from a Moroccan phytochemical database (MPDB) derived from aromatic & medicinal plants. Bioinformation. 2023 Dec 31; 19(12): 1217-1224. doi: 10.6026/973206300191217. PMID: 38250527; PMCID: PMC10794753. Elkhattabi, L., Zouhdi, S., Mousstead, F., Kettani, A., Barakat, A., Saile, R. Molecular docking analysis of PPARγ with phytochemicals from Moroccan medicinal plants. Bioinformation. 2023 Jul 31; 19(7): 795-806. doi: 10.6026/97320630019795. PMID: 37901293; PMCID: PMC10605085. Charoute, H., Elkarhat, Z., Elkhattabi, L., ...Rouba, H., Barakat, A. Computational screening of potential drugs against COVID-19 disease: the Neuropilin-1 receptor as a molecular target. VirusDisease, 2022, 33(1), pp. 23–31. doi: 10.1007/s13337-021-00751-x. Elkhattabi, L., Charoute, H., Saile, R., Barakat, A. Computational approach revealed potential affinity of antiasthmatics against receptor binding domain of 2019-nCoV spike glycoprotein. ChemRxiv. Preprint, 2020. Elkarhat, Z., Charoute, H., Elkhattabi, L., Barakat, A., Rouba, H. Journal of Biomolecular Structure and Dynamics, 2022, 40(1), pp. 361–374. Potential inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase protein: molecular docking, molecular dynamics simulations, and MM-PBSA analyses. Journal of Biomolecular Structure & Dynamics 40 (1): 361 74. Benhsaien, I., Essadssi, S., Elkhattabi, L., ...Badou, A., Omenn syndrome caused by a novel homozygous mutation in the recombination activating gene. Barakat, A. Immunobiology, 2021, 226(3), 152090. DOI: 10.1016/j.imbio.2021.152090. Elrharchi, S., Riahi, Z., Salime, S., Elkhattabi, L., ...Petit, C., Barakat, A. Human Heredity, 2021, 85(1), pp. 35–39. Novel mutation in AIFM1 gene associated with X-linked deafness in a Moroccan family. doi: 10.1159/000512712. Epub 2021 Jan 22. Elkarhat, Z., Elkhattabi, L., Hicham C., Imane M., Errouagui A., Francis C., Boubker N., Abdelhamid B., et Hassan R. 2020. "Identification of deleterious missense variants of the human Piwi-like RNA-mediated gene silencing 1 gene and their impact on PAZ domain structure, stability, flexibility, and dimension: In silico analysis." Journal of Biomolecular Structure & Dynamics 38 (15): 4600 4606. https://doi.org/10.1080/07391102.2019.1678522. Elkhattabi, L., Morjane, I., Charoute, H., Saile, R., Barakat, A. Computational screening and analysis of the functional and structural impact of SNPs of the human RETN gene associated with type 2 diabetes. Atherosclerosis, 315, e199–e200 (2020). doi: 10.1016/j.atherosclerosis.2020.10.622 / https://doi.org/10.1016/j.atherosclerosis.2020.10.622 Bousfiha, A., Riahi, Z., Elkhattabi, L., ...Petit, C., Barakat, A. Further evidence for the implication of the MET gene in non-syndromic autosomal recessive deafness. Human Heredity, 2020, 84(3), pp. 109–116. doi: 10.1159/000503450. Epub 2019 Dec 4. Morjane, I., Charoute, H., Ouatou, S., Elkhattabi, L., ...Rouba, H., Barakat, A. Association of c.56C > G (rs3135506) Apolipoprotein A5 gene polymorphism with coronary artery disease in Moroccan subjects: A case-control study and an updated meta-analysis. Cardiology Research and Practice, 2020, 2020, 5981971, doi: 10.1155/2020/5981971. eCollection 2020. Essadssi, S., Krami, M., Elkhattabi, L., ...Rouba, H., Barakat, A. Journal of Immunology Research, 2019, 2019, 5902391. Computational analysis of nsSNPs of ADA gene in severe combined immunodeficiency using molecular modeling and dynamics simulation. 

Elkhattabi, Lamiae, Imane Morjane, Hicham Charoute, Soumaya Amghar, Hind Bouafi, Zouhair Elkarhat, Rachid Saile, Hassan Rouba, et Abdelhamid Barakat. 2019. "In silico analysis of coding/noncoding SNPs of the human RETN gene and characterization of their impact on resistin stability and structure." Journal of Diabetes Research 2019 (May): 4951627. https://doi.org/10.1155/2019/4951627. B. Belkady; L. Elkhattabi; Z. Elkarhat; L. Zarouf; L. Razoki; J. Aboulfaraj; S. Nassereddine; R. Cadi; H. Rouba; A. Barakat. Chromosomal abnormalities in patients with intellectual disability: A 21-year retrospective study. Human Heredity, 2019, 83(5), pp. 274–282. https://doi.org/10.1159/000499710.
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