Vous essayez de contacter : Mr EL BRAHMI Nabil


ID-IRC : 2314050836

Chercheur Photo
EL BRAHMI Nabil
Professeur d’habilité

Spécialité : Chimie

Faculté Euro-Med de Génie - Fès

Domaine de Maîtrise :
Biopathologie et Recherche Biomédicale**

Domaine d’intérêt :
Biopathologie et Recherche Biomédicale**

Les publications :

An overview on the synthesis and anticancer properties of ethacrynic acid and their analogues, N. El Brahmi, A. El Abbouchi, S. El Kazzouli, Results Chem. 2023, 101117. (IF = 2.3). In vitro Cytotoxic, Antioxidant, Hemolytic and Cytoprotective Potential of Promising Ethacrynic Acid Derivatives A. Idir, N. Bouchmaa, A. El Abbouchi, N. El Brahmi, R. Ben Mrid, Y. Bouargalne, H. Ait Mouse, M. Nhiri, M. Bousmina, S. El Kazzouli, A. Zyad, Mor. J. Chem., 2023, 11, 657-673. Improvement of the Chemical Reactivity of Michael Acceptor of Ethacrynic Acid Correlates with Antiproliferative Activities. A. El Abbouchi, N. El Brahmi, M-A. Hiebel, H. Ghammaz, E. El Fahime, J. Bignon, G. Guillaumet, F. Suzenet, S. El Kazzouli, Molecules 2023, 28, 910 (IF = 4.93). Synthesis, Anticancer Activities and Molecular Docking Studies of a Novel Class of 2-Phenyl-5,6,7,8-tetrahydroimidazo [1,2- b]pyridazine Derivatives Bearing Sulfonamides. O. Bourzikat, A. El Abbouchi , H. Ghammaz , N. El Brahmi, E. El Fahime , A. Paris , R. Daniellou , F. Suzenet , G. Guillaumet , S. El Kazzouli, Molecules 2022, 27, 5238 (IF = 4.93). Synthesis and Evaluation of a Novel Class of Ethacrynic Acid Derivatives Containing Triazoles as Potent Anticancer Agents. A. El Abbouchi, N. El Brahmi, M-A. Hiebel, J. Bignon, G. Guillaumet, F. Suzenet, S. El Kazzouli. Bioorg. Chem. 2021, 115, 105293 (IF = 5.27). Design, Synthesis and Biological Evaluation of Ethacrynic Acid Derivatives Bearing Sulfonamides as Potent Anti-Cancer Agents. A. El Abbouchi, N. El Brahmi, M-A. Hiebel, J. Bignon, G. Guillaumet, F. Suzenet, S. El Kazzouli. Bioorg. Med. Chem. Lett. 2020, 30, 127426 (IF = 2.7). First-in-Class Combination Therapy of a Copper(II) Metallo-Phosphorus Dendrimer with Cytotoxic Agents. S. Mignani, N. El Brahmi, T. Cresteil, J. P. Majoral. Oncology, 2018, 94(5), 324-328 (IF = 2.6). Original Multivalent Gold(III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents. S. Mignani, N. El Brahmi, S. El Kazzouli, R. Laurent, S. Ladeira, A. M. Caminade, E. Pedziwiatr-Werbicka, E. Szewczyk, M. Bryszewska, M. Bousmina, T. Cresteil, J. P. Majoral. Mol. Pharm. 2017, 14, 11, 4087-4097 (IF = 4.39). Anticancer Copper(II) Phosphorus Dendrimers are Potent Proapoptotic Bax Activators. S. Mignani, N. El Brahmi, L. Eloy, J. Poupon, V. Nicolas, A. Steinmetz, S. El Kazzouli, M. Bousmina, M. Blanchard-Desce, A. M. Caminade, J. P. Majoral, T. Cresteil. Eur. J. Med. Chem. 2017, 132, 142-156 (IF = 4.83). A Novel Class of Ethacrynic Acid Derivatives as Promising Druggable Potent Generation of Anticancer Agents with Established Mechanism of Action. S. Mignani, N. El Brahmi, S. El Kazzouli, L. Eloy, D. Courillaud, J. Caron, M. M. Bousmina, A. M. Caminade, T. Cresteil, J. P. Majoral. Eur. J. Med. Chem. 2016, 122, 656-673 (IF = 4.83). Investigations on Dendrimer Space Reveal Solid and Liquid Tumor Growth-inhibition by Original Phosphorus-based Dendrimers and the Corresponding Monomers and Dendrons with Ethacrynic Acid Motifs. N. El Brahmi, S. Mignani, J. Caron, S. El Kazzouli, M. Bousmina, A. M. Caminade, T. Cresteil, J. P. Majoral. Nanoscale. 2015, 7, 3915-3922 (IF = 6.97). Comparative EPR Studies of Cu(II)-conjugated Phosphorous-dendrimers in the Absence and Presence of Normal and Cancer Cells. M. F. Ottaviani, N. El Brahmi, M. Cangiotti, C. Coppola, F. Buccella, T. Cresteil, S. Mignani, A. M. Caminade, J. P. Costes, J. P. Majoral. RCS Advences. 2014, 4, 36573-36583 (IF = 3.05). P8) Copper in Dendrimer Synthesis and Applications of Copper-dendrimer Systems in Catalysis: A Concise Overview. N. El Brahmi, S. El Kazzouli, S. Mignani, M. Bousmina and J-P. Majoral. Tetrahedron. 2013, 69, 3103-3133 (IF = 2.38). Microwave-assisted Suzuki-Miyaura Cross-coupling of free (NH) 3-Bromoindazoles. A. Ben-Yahia, M. Nass, N. El Brahmi, S. El Kazzouli, J-P. Majoral, E. Essassi, G. Guillaumet, Curr. Org. Chem. 2013, 17, 304-309 (IF = 2.03). Original Multivalent Copper(II)-conjugated Phosphorus Dendrimers and Corresponding Mononuclear Copper(II) Complexes with Antitumoral Activities. N. El Brahmi, S. El Kazzouli, S. Mignani, E. M. Essassi, G. Aubert, R. Laurent, A. M. Caminade, M. Bousmina, T. Cresteil, J-P. Majoral; Mol. Pharmaceutics. 2013, 10, 1459-1464 (IF = 4.39). From Metallodrugs to Metallodendrimers for Nanotherapy in Oncology: A Concise Overview. S. El Kazzouli, N. El Brahmi, S. Mignani, M. Bousmina, J-P. Majoral; Curr. Med. Chem. 2012, 19, 4995-5010 (IF = 3.89).
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