Domaine de Maîtrise :
Biopathologie et Recherche Biomédicale

Domaine d’intérêt :
Recherche Clinique, Biopathologie et Recherche Biomédicale**

Les publications :
Amrani M., K. Lalaoui, M. El Mzibri, L. Rouas, L. Benkirane, N. Lamaalmi, A. Regragui, L. Gamra, M.A. Belabbas. 2002. Place de la cytologie cervicale et du typage moléculaire des PapillomaVirus Humains (PVH) : résultats d’une étude critique marocaine. Maroc Médical. 24 : 206-211 Lalaoui, K., El Mzibri, M., Amrani, M., Belabbas, M.A. and P.A. Lazo. 2003. Human papillomavirus DNA in cervical lesions from Morocco and its implications for cancer control. Clinical Microbiology and Infection. 9: 144-148. Amrani, M., Lalaoui, K., El Mzibri, M., Lazo, P. and M.A. Belabbas. 2003. Molecular detection of human papillomavirus in 594 uterine cervix samples from Moroccan women (147 biopsies and 447 swabs. Journal of Clinical Virology. 27: 286-295. El Mzibri, M., Amrani, M. Belabbas, M.A. et K. Lalaoui. 2004. Dépistage moléculaire des papillomavirus humains génitaux dans une population marocaine. Journal Marocain des Sciences Nucléaires.2 : 48-53. Lalaoui, K., El Mzibri, M., Laget, M., Guiraud-Dauriac, H., Duménil, G. et M. Hmamouchi. 2004. Evaluation de l'effet antiprolifératif de quelques plantes marocaines sur une lignée cancéreuse du col de l'utérus. Maroc Médical. 26 (2) : 89-93. Meftah El Khair M, M. El Mzibri, R. Ait Mhand, A. Benider, N. Benchekroun, M. El fahime, M.N. Benchekroun and M.M. Ennaji. 2009. Molecular detection and genotyping of human papillomavirus in cervical carcinoma biopsies in an area of high incidence of cancer from Moroccan women. Journal of Medical Virology. 81: 678-684. Meftah el khair, M., M. EL Mzibri, R. Ait Mhand, A. Benider, N. Benchekroun, M.N. Benchkroun, M.M. Ennaji. Molecular characterisation of oncogenic human papillomavirus in uterine cervix samples from Moroccan women. Proceeding of the 3rd international congress of Biochemistry. Marrakech: 20-24 April 2009. El Mzibri, M., M. Amrani, M. Meftah El Khair, M. Attaleb, H. Jaddi, M.M. Ennaji, B.K. Khan and M.A. Belabbas. 2009. Prevalence of human papillomavirus infection in malignant lesions of the uterine cervix in Morocco. World Journal of Nuclear Medicine. 8:192-196. Attaleb, M., W. El hamadani, M. Khyatti, L. Benbacer, N. Benchekroun, A. Benider, M. Amrani and M. El Mzibri. 2009. Status of p16INK4a and E-Cadherin genes promoter methylation in Moroccan patients with cervical carcinoma. Oncol. Res. 18: 185-192. Meftah El khair, M., MM. Ennaji, R. El kebbaj, R. Ait Mhand, M. Attaleb and M. El Mzibri. 2009. p53 codon 72 polymorphism and risk of cervical carcinoma in Moroccan Women. Medical oncology. Septembre 23. Meftah El khair, M., R. Ait Mhand, M. El Mzibri and MM. Ennaji. Risk factors for cervical cancer in Morocco. 2009. Cellular and Molecular Biology. Volume 55. Merghoub, N., L. Benbacer, S. Amzazi, H. Morjani and M. El Mzibri. 2009. Cytotoxic effect of some Moroccan medicinal plant extracts on human cervical cell lines. Journal of Medicinal Plant Research. 3 : 1045-1050. Ameziane-El-Hassani, R., M. Boufraqech, O. Lagente-Chevallier, U. Weyemi, M. Talbot, D. Métivier, F. Courtin, J.M. Bidart,, M. El Mzibri, M. Schlumberger and C. Dupuy. 2010. Role of H2O2 in RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells. Cancer Res. 70: 4123-4132 El Hamdani W., M. Amrani, M. Attaleb, N. Laantri, M.M. Ennaji, M. Khyatti and M. El Mzibri. 2010. EGFR, p16INK4a and E-Cadherin immuno-histochemistry and EGFR point mutations analyses in invasive cervical cancer specimens from Moroccan women. Cellular and Molecular Biology (Noisy-le-grand). 56 : 1373-1384. Alhamany Z., M. El Mzibri, A. Kharbach, A. Malihy, R. Abouqal, H. Jaddi, A. Benomar, M. Attaleb, N. Lamalmi and N. Cherradi. 2010. Prevalence of Human papillomavirus genotype among Moroccan women during a local screening program. Journal of Infection in Developing Countries. 4(11): 732-739. Naji F., M. Attaleb, A. Daghi, N. Laantri, N. Benchakroun, H. Azzedoug, M. El Mzibri and M. Khyatti. 2010. Epidermal Growth Factor Receptor point mutation in Moroccan patients with Nasopharyngeal Carcinoma. Cellular and Molecular Biology. 56. Suppl:OL1442-6 Laantri N., M. Attaleb, M. Kandil, F. Naji, T. Mouttaki, R. Dardari, K. Belghmi, N. Benchakroun, M. El Mzibri and M. Khyatti. 2011. Human papillomavirus detection in Moroccan patients with nasopharyngeal carcinoma. Infectious Agents and Cancer. 6: 3 Merghoub N, L. Benbacer, H. El Btaouri, H. Ait Benhassou, C. Terryn, M. Attaleb, C. Madoulet, A. Benjouad, M. El Mzibri, H. Morjani and Amzazi S. 2011. In vitro antiproliferative effect and induction of apoptosis by Retama monosperma l. extract in human cervical cancer cells. Cell Mol Biol (Noisy-le-grand). Oct 15;Suppl 57:OL1581-91. El Mzibri M., M. Attaleb, R. Ameziane El Hassani, M. Khyatti, L. Benbacer, M.M. Ennaji and M. Amrani and. Evaluation of p53, p16INK4a and E-cadherin status as biomarkers for cervical cancer diagnosis. In "Cervical cancer », ISBN 979-953-307-054-3. Intech Open Acces Publisher 2012. Benbacer, L., N. Merghoub, H. El Btaouri, S. Gmouh, M. Attaleb, H. Morjani, S. Amzazi and M. El Mzibri. Antiproliferative effect and induction of apoptosis by Inula viscosa L. and Retama monosperma L. extracts in human cervical cancer cells. In "Cervical cancer », ISBN 979-953-307-054-3. Intech Open Acces Publisher 2012. Berrada N, S. Amzazi, R. Ameziane El Hassani, L. Benbacer, M. El Mzibri, M. Khyatti, J. Chafiki, M. Abbar, A. Al Bouzidi, A. Ameur and M. Attaleb. 2012. Epigenetic alterations of adenomatous polyposis coli (apc), retinoic acid receptor beta (rarβ) and survivin genes in tumor tissues and voided urine of bladder cancer patients. Cell Mol Biol. 2012 Sep 10; Suppl.58: OL1744-51. Qmichou Z., M. Khyatti, M. Berraho, M.M. Ennaji, L. Benbacer, C. Nejjari, N. Benjaafar, A. Benider, M. Attaleb and M. El Mzibri. 2013. Analysis of mutations in the E6 oncogene of Human Papillomavirus 16 in cervical cancer isolates from Moroccan women. BMC Infectious Diseases. 13: 378 Berrada N, S. Amzazi, Z. Qmichou, R. Ameziane El Hassani, L. Benbacer, M. El Mzibri, M. Khyatti, J. Chafiki, M. Abbar, A. Al Bouzidi, A. Ameur and M. Attaleb. 2013. Human papillomavirus detection in Moroccan patients with Bladder cancer. Journal of Infect in Developing Countries. 7: 586-592. Qmichou, Z., M.M. Ennaji, M. Amrani, E.M. El Fahime, M. Melloul, M. Meftah El khair, M. El Mzibri, M. Khyatti and M. Attaleb. 2013. Molecular characterization of HPV16 E6 and E7 variants among women with cervical cancer in Morocco. British Microbiology Research Journal. 3(4): 692-705 Berrada N, S. Amzazi, Z. Ameziane El Hassani, L. Benbacer, M. El Mzibri, M. Khyatti, J. Chafiki, M. Abbar, A. Al Bouzidi, A. Ameur and M. Attaleb. 2013. No evidence of correlation between p53 codon 72 polymorphism and risk of bladder cancer in Moroccan patients. Clinical Cancer Investigation Journal. 2: 302-306. Slaoui M., R. Razine, A. Ibrahimi, M. Attaleb, M. El Mzibri and M. Amrani. 2014. Bresat cancer in Morocco: A litterature review. Asian Pacific Journal of Cancer Prevention. 15:1067-74. Elamrani, A., M.M. Ennaji, M. Benhessou, M. Attaleb, M. El Mzibri, M. Corbex, T. Massimo, T. Gheit and M. Khyatti. 2014. Detection of Human Papillomavirus DNA in Breast Cancer in Moroccan Woman. Annals of Oncology. Volume 24, suppl 3. pp. iii45. El Amrani M., K. Moumad, M. Attaleb, M. Benhassou, A. Försti, M.M. Ennaji, M. El Mzibri and M. Khyatti. Absence of CHEK2 1100delC, R145W and I157T Mutations in Breast Cancer in a Moroccan Population. 2014. Journal of Cancer Research and Treatment, 2: 6-9 Slaoui, M., M. El Mzibri, R. Razine, Z. Qmichou, M. Attaleb and M. Amrani. Detection of MMTV-Like sequences in Moroccan breast cancer cases. Infectious Agents and Cancer 2014, 9:37. Magloire ALB, Z. Qmichou, M. Mouallif, M. Attaleb, M. El Mzibri, L. Hilali, D. Moukassa and My M. Ennaji. 2015. Human papillomavirus genotypes distribution by cervical cytologic status among women attending the general hospital of loandjili, pointe noire, southwest congo. Journal of Medical Virology. 87 : 1769-1776. Ennaji, M.M., A. El Amrani, M. El Mzibri, A. Ben Hassou, S. Boughribil, M. Khyatti. Cancer du sein : génétique, facteurs de risques et étiologie virale" avec l'ISBN 978-3-8416-6098-5. Editions universitaires européennes. 2015. 139pp. Merghoub N., H. El Btaouri, L. Benbacer, S. Gmouh, C. Trentesaux, B. Brassart, C. Terryn, M. Attaleb, C. Madoulet, A. Benjouad, S. Amzazi, M. El Mzibri & H. Morjani. 2016. Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance. Nutrition and Cancer. 68(1): 131-43. DOI: 10.1080/01635581.2016.1115105 Zoa Assoumou S, A. Ndjoyi Mbiguino, B. Mabika Mabika, S. Nguizi Ogoula, M. El Mzibri, A. Khattabi, MM. Ennaji. 2016. Human papillomavirus genotypes distribution among Gabonese women with normal cytology and cervical abnormalities. Infect Agent Cancer. 15: 11:2. doi: 10.1186/s13027-016-0046-0. eCollection 2016. El Aliani, A. H. Jaddi, M.M. Ennaji, M. EL Mzibri. 2016. Recent Advances in Human Papillomavirus Detection and Genotyping. British Microbiology Research Journal. 11(6): 1-22. Kaabouche M., M. El Mzibri., S. El Kaandri, R. Ameziane El Hassani, A. Al Bouzidi. 2016. Thyroid Cancer: State of Art in Morocco. Thyroid Disorders Ther. 5:197. doi: 10.4172/2167-7948.1000197. Mouh El Basri F., M. Slaoui, M. El Mzibri and M. Amrani. Recent Progress in Triple Negative Breast Cancer Research. Asian Pac J Cancer Prev. 2016;17(4):1595-608 Azouzi N., J. Cailloux, J.M. Cazarin, J.A. Knauf, J. Cracchiolo, A. Al Ghuzlan, D. Hartl, M. Polak, A. Carre, M. El Mzibri, A. Filali-Maltouf, A. Al Bouzidi, M. Schlumberger, J.A. Fagin, R. Ameziane-El-Hassani and C. Dupuy. 2016. NADPH oxidase NOX4 is a critical mediator of BRAFV600E-induced down regulation of the sodium iodide symporter in papillary thyroid carcinomas. Antioxid Redox Signal. PMID: 27401113 Hadami K., R. Ameziane El Hassani, A. Ameur, N. Dakka, M. Abbar, A. Al Bouzidi, M. Attaleb and M. El Mzibri. 2016. No association between GPX1 Pro189Leu polymorphism and the occurrence of bladder cancer in Morocco. Cellular and Molecular Biology. 62(14):38-43. Merghoub N., H. El Btaouri, L. Benbacer, S. Gmouh, C. Trentesaux, B. Brassart, M. Attaleb, C. Madoulet, T. Wenner, S. Amzazi, H. Morjani & M. El Mzibri. 2017. Tomentosin induces telomere shortening and caspase dependent apoptosis in cervical cancer cells. Journal of Cellular Biochemistry. 118(7):1689-1698. doi: 10.1002/jcb.25826. Berraho M., A. Amarti-Riffi, M. El Mzibri, R. Bezad, N. Benjaafar, A. Benideer, N. Matar, Z. Qmichou, N. Abda, M. Attaleb, K. Znati, H. El Fatemi, K. Bendahhou, M. Obtel, A. Filali Adib, S. Mathoulin-Pelissier, C. Nejjari. HPV and cofactors for invasive cervical cancer in Morocco: a multicentre case-control study. BMC Cancer. 2017 Jun 20;17(1):435. doi: 10.1186/s12885-017-3425-z El Hamdani W., K. Hadami, M. Bensaid. H. El Ahanidi, A. Ameur, A. Filali Maltouf, M. Abbar, M. Attaleb, A. Al Bouzidi and M. El Mzibri. 2017. Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with Bladder Cancer. Cell Mol Biol. 63:75-81 El Aliani Aissam, Abdelaziz Elalaoui, Imane Chaoui, My Mustapha Ennaji, Mohammed Attaleb and Mohammed El Mzibri. 2017. Naturally-occurring capsid protein variants L1 of human papillomavirus genotype 16 in Morocco. Bioinformation. 13(8): 241-248. Habyarimana Thierry, Mohammed Attaleb, Pacifique Mugenzi, Jean Baptiste Mazarati, Youssef Bakri, Mohammed El Mzibri. Association of p53 codon 72 polymorphism with breast cancer in Rwandese population. Pathobiology. 2017 Nov 1. doi: 10.1159/000481664 Habyarimana Thierry, Bakri Youssef, Mugenzi Pacifique, Mazarati Jean Baptiste, Attaleb Mohammed and El Mzibiri Mohammed. 2018. Association between Glutathione Peroxidase 1 codon 198 variant and the occurrence of breast cancer in Rwanda. Molecular Genetics & Genomic Medicine. 2018 Feb 6. doi: 10.1002/mgg3.367. Habyarimana Thierry, Mohammed Attaleb, Jean Baptiste Mazarati, Youssef Bakri and Mohammed El Mzibri. 2018. Detection of human papillomavirus DNA in tumors from Rwandese breast cancer patients. Breast Cancer. 2018 Mar;25(2):127-133. doi: 10.1007/s12282-018-0831-2 Habyarimana T., M. Attaleb, P. Mugenzi, J.B. Mazarati, Y. Bakri, M. El Mzibri. 2018. The CHEK2 germiline mutations play an irrelevant role among familial and sporadic breast cancer patients in Rwandan population. Asian Pacific Journal of Cancer Prevention. 19(2):375-379. El Amrani Amal, Tarik Gheit, Mustapha Benhessou, Sandrine McKay-Chopin, Mohammed Attaleb, Souha Sahraoui, Mohammed El Mzibri, Marilys Corbex, Massimo Tommasino, Meriem Khyatti. Prevalence of mucosal and cutaneous human papillomavirus in Moroccan breast cancer. Papillomavirus Research. S2405-8521(17)30096-4. Zouré A, M. Slaoui, A.H. Bambara, A.Y. Sawadogo, T.R. Compaoré, N.L.M. Ouédraogo, M. Attaleb, S.S. Traoré, M. El Mzibri, J. Simporé and Y. Bakri. Absence of BRCA1 c.68_69delAG, c.181T>G, c.798_799delTT and 943ins10 mutations in families with breast cancer history in Burkina Faso. Journal of Public Health in Africa 2018; 9:663 Slaoui Meriem, Abdou Azaque Zoure, Fatima Zahra Mouh, Youssef Bensouda, Mohammed El Mzibri, Youssef Bakri, Mariam Amrani. Outcome of Inflammatory Breast Cancer in Moroccan patients: clinical, molecular and pathological characteristics of 219 cases from the Institut National d'Oncologie. BMC Cancer. 2018. 18(1):713. doi: 10.1186/s12885-018-4634-9. Hadami K., N. Dakka, M. Bensaid, R. Ahanidi, A. Ameur, M. Abbar, A. Al Bouzidi, M. Attaleb and M. El Mzibri. 2018. GST-pi expression and promoter methylation in Moroccan patients with urothelial bladder cancer. Molecular Genetics & Genomic Medicine. 2018 Jul 24. doi: 10.1002/mgg3.449 Makrane Hanane, Mohcine El messaoudi, Ahmed Melhaoui, Mohammed El mzibri, Laila Benbacer and Mohammed Aziz. Cytotoxicity of the aqueous extract and organic fractions from Origanum majorana on human breast cell lines MDA-MB-231 and human colon cell lines HT-29. Adv Pharmacol Sci. 2018 Aug 23;2018:3297193. doi: 10.1155/2018/3297193. eCollection 2018. El Mzibri M., I. Chaoui, M. Khyatti and M. Attaleb. 2019. The Molecular Basis of Viro-Induced Carcinogenesis. 2019. Frontiers in Science and Engineering. 8 (2): 39-52 Ahanidi H., C. Hafidi Alaoui, M. Bensaid, M. El Mzibri, A. Ameur, M. Abbar, A. Al Bouzidi and M. Attaleb. 2019. Assessment of molecular biomarkers for bladder cancer diagnosis, grading and prognosis. Frontiers in Science and Engineering. 8 (2): 53-61 Hadami K., N. Dakka, M. Bensaid, A. Ameur, H. Chahdi, M. Oukabli, A. Al Bouzidi, M. Attaleb and M. El Mzibri. 2019. Evaluation of GPX1 Pro198Leu polymorphism, GSTP1 expression and gene promoter methylation in Moroccan patients with bladder cancer. 2019. Frontiers in Science and Engineering. 8 (2): 62-78 Bourhia Mohammed, Fatima Ezzahra Laasri, Riaz Ullah, Abdelaaty Shahat, Mohammed El Mzibri, Said Gmouh, Laila Benbacer, Aicha Boukhriss, Hind Aourik. 2019. Antioxidant and Antiproliferative activities of bioactive compounds contained in Rosmarinus officinalis used in the Mediterranean diet. Evidence-Based Complementary and Alternative Medicine. 2019 Nov 16;2019:7623830. doi: 10.1155/2019/7623830. Khaali Wafa, Amina Gihbid, Amal ElAmrani, Imane Chaoui, Mohammed Attaleb, Mustapha Benhassou, Khalid Belghmi, Mohammed El Mzibri, Meriem Khyatti. 2019. Prevalence, Genotype Distribution and Risk Factors of Human Papillomavirus in Moroccan Women. Arch Clin Biomed Res: 3 (6): 397-407. Bourhia Mohammed, Fatima Ezzahra Laasri, Agmih Kaoutar, Mohamed El Mzibri, Said Gmouh, Naima Khlil and Laila Benbacer. Phytochemistry, antioxidant activity, antiproliferative effect and acute toxicity testing of two Moroccan Aristolochia species. Evidence-Based Complementary and Alternative Medicine. ID 9710876, 8 pages. doi.org/10.1155/2019/9710876 Abumsimir Berjas, Mohammed Mrabti, Abdelilah Laraqui, Ahmed Ameur, Saad Ibnsouda Koraishi, Mohammed El Mzibri, Mohammed Nabil Benchekroun, Hlima Bessi, Ikram Tiabi, Ihsan Almahasneh, Moulay Mustapha Ennaji. 2019. Most frequent mutational events of home box 13 gene in prostate cancer biopsies and correlation with tumor characteristics. Meta Gene. 2020. 23.100637. DOI. 10.1016/j.mgene.100637. Fatima Zahra Mouh, Meriem Slaoui, Rachid Razine, Mohammed El Mzibri and Mariam Amrani. Clinicopathological, Epidemiological, Treatment and Event Free Survival characteristics in a Moroccan Population of Triple-Negative Breast Cancer. Accepté avec modifications pour publication dans Breast Cancer: Basic and Clinical Research.