Domaine de Maîtrise :
Biopathologie et Recherche Biomédicale

Domaine d’intérêt :
Biopathologie et Recherche Biomédicale**

Les publications :
1. Sánchez-Hernández S; Gutierrez-Guerrero A; Martín-Guerra R; Cortijo-Gutierrez M; M Tristán‐Manzano M; Rodriguez-Perales S; Sanchez L; Garcia-Perez JL; Chato-Astrain J; Fernandez-Valades R; Carrillo Galvez AB; Anderson P; Montes R; Real PJ; Martin F; Benabdellah K. The IS2 element improves transcription efficiency of integration-deficient lentiviral vectors (IDLVs) episomes. MOLECULAR THERAPY-NUCLEIC ACIDS. (2018). -------------------------------------------------------------------------------------------------------------------------------------- 2. Gutierrez-Guerrero Alejandra, Sanchez-Hernandez Sabina, Galvani Giuseppe Pinedo-Gomez Javier, Sanchez-Gilabert Almudena, Martin-Guerra Rocio Cobo Marien, Gregory Philip, Holmes Michael, Martin Francisco*, Benabdellah Karim* (*share senior authorship). Comparison of ZFNs versus CRISPR specific nucleases for genome edition of the Wiskott-Aldrich Syndrome locus. HUMAN GENE THERAPY (2017). -------------------------------------------------------------------------------------------------------------------------------------- 3. Marin-Bañasco C; Benabdellah K; Melero-Jerez C; Oliver B; Pinto-Medel MJ; Hurtado-Guerrero I; de Castro F; Clemente D; Fernández O; Martin F; Leyva L; Suardíaz M. Gene therapy with mesenchymal stem cells expressing FN-ß ameliorates neuroinflammation in experimental models of multiple sclerosis. BRITISH JOURNAL OF PHARMACOLOGY. (2017). -------------------------------------------------------------------------------------------------------------------------------------- 4. Benabdellah K; Muñoz P; Cobo M; Gutierrez-Guerrero A; Sánchez Hernández S; Garcia-Perez A; Anderson P; Carrillo-Gálvez AB; Toscano MG; Martin F. Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells. SCIENTIFIC REPORTS. (2016). -------------------------------------------------------------------------------------------------------------------------------------- 5. Martin F; Sánchez-Hernández S; Gutiérrez-Guerrero A; Pinedo-Gomez J; Benabdellah K. Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016). -------------------------------------------------------------------------------------------------------------------------------------- 6. Toscano MG; Muñoz P; Sánchez-Gilabert A; Cobo M; Benabdellah K; Anderson P; Ramos-Mejía V; Real PJ; Neth O; Molinos-Quintana A; Gregory PD; Holmes MC; Martin F. Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model. MOLECULAR THERAPY (2016). -------------------------------------------------------------------------------------------------------------------------------------- 7. Barriocanal-Casado E; Cueto-Ureña C; Benabdellah K; Gutiérrez-Guerrero A; Cobo M; Hidalgo-Gutiérrez A; Rodríguez-Sevilla JJ; Martín F; López LC. Gene Therapy Corrects Mitochondrial Dysfunction in Hematopoietic Progenitor Cells and Fibroblasts from Coq9R239X Mice PLOS ONE (2016). -------------------------------------------------------------------------------------------------------------------------------------- 8. F Martín; A. Gutierrez-Guerrero; S. Sánchez; G. Galvani; Benabdellah K Genome editing: An alternative to retroviral vectors for Wiskott-Aldrich Syndrome (WAS) Gene Therapy?. Expert Opinion on Orphan Drug (2016) -------------------------------------------------------------------------------------------------------------------------------------- 9. Carrillo-Galvez AB; Cobo M; Cuevas-Ocaña S; Gutiérrez-Guerrero A; Sánchez-Gilabert A; Bongarzone P; García-Pérez A; Muñoz P; Benabdellah K; Toscano MG; Martín F; Anderson P. Mesenchymal stromal cells express GARP/LRRC32 on their surface: effects on their biology and immunomodulatory capacity STEM CELLS (2015). -------------------------------------------------------------------------------------------------------------------------------------- 10. Benabdellah K; Cobo M; Muñoz P; Toscano MG; Martin F. A chimeric HS4-SAR insulator (IS2) that prevents silencing and enhances expression of lentiviral vectors in pluripotent stem cells.. PLoS One. (2014). --------------------------------------------------------------------------------------------------------------------------------------