Domaine de Maîtrise :
Biopathologie et Recherche Biomédicale

Domaine d’intérêt :
Recherche Clinique, Biopathologie et Recherche Biomédicale**

Les publications :
1- Abdeslam Jaafari , El Mostapha Rakib , Hassan Ait Mouse , Lahcen Ait M’bark , Chouaib Benbakhta , Abdelali Boulli , Aziz Abbad & Abdelmajid Zyad * “Chemical composition and antitumor activity of different wild varieties of Moroccan thyme Revista Brasileira de Farmacognosia Brazilian Journal of Pharmacognosy17(4): 477-491, Out./Dez. 2007 » 2- Abdeslam Jaafari, Hassan Ait Mouse, Lahcen Ait M’bark, Mounir Tilaoui, Mohamed Elhansali, Michel Lepoivre & Abdelmajid Zyad “Differential antitumor effect of essential oils and their major components of Thymus broussonettii: Relationship to cell cycle and apoptosis induction” Herba Polinica 2009 3- Abdeslam Jaafari; Mounir Tilaoui; Hassan Ait Mouse; Lahcen Ait M'bark; Rachida Aboufatima; Abderrahmane Chait; Michel Lepoivre; Abdelmajid Zyad. Comparative study of the antitumor effect of natural monoterpenes: relationship to cell cycle analysis. Rev. bras. farmacogn. [online]. 2012, vol.22, n.3, pp. 534-540. 4- L. Ait M’Barek ,H. Ait Mouse, A. Jaâfari,, R. Aboufatima, A. Benharref, M. Kamal, J. Bénard, N. El Abbadi ,M. Bensalah, A. Gamouh ,A. Chait, A. Dalal and A. Zyad “Cytotoxic effect of essential oil of thyme (Thymus broussonettii) on the IGR-OV1 tumor cells resistant to chemotherapy”. Brazilian Journal of Medical and Biological Research (2007) 40: 1537-1544 5- Mounir Tilaoui; Hassan Ait Mouse; Abdeslam Jaafari; Rachida Aboufatima; Abderrahman Chait; Abdelmajid Zyad. Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba. Rev. bras. farmacogn. [online]. 2011, vol.21, n.4, pp. 781-785. 6- Hassan Ait Mouse; Mounir Tilaoui; Abdeslam Jaafari; Lahcen Ait M'barek; Rachida Aboufatima; Abderrahmane Chait; Abdelmajid Zyad.Evaluation of the in vitro and in vivo anticancer properties of Moroccan propolis extracts. Rev. bras. farmacogn. 2012, vol.22, n.3, pp. 558-567. 7- Mounir Tilaoui, Hassan Ait Mouse , Abdeslam Jaafari and Abdelmajid Zyad. Differential Effect of Artemisinin Against Cancer Cell Lines. Nat. Prod. Bioprospect. (2014) 4:189–196 DOI 10.1007/s13659-014-0024-4 8. Mounir Tilaoui, Hassan Ait Mouse, Abdeslam Jaafari, Abdelmajid Zyad Comparative Phytochemical Analysis of Essential Oils from Different Biological Parts of Artemisia herba alba and Their Cytotoxic Effect on Cancer Cells. Cancer Cells. PLoS ONE 10(7): e0131799. 9. Moulay Ali Oukerrou, Mounir Tilaoui, Hassan Ait Mouse, Inass Leouifoudi, Abdeslam Jaafari, and Abdelmajid Zyad. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological Sciences.Volume 2017, Article ID 7801924, 10 pages‬‬‬‬‬‬‬‬ 10. Abdelmajid Zyad, Mounir Tilaoui, Abdeslam Jaafari |Moulay Ali Oukerrou, Hassan Ait Mouse. More insights into the pharmacological effects of artemisinin. Phytotherapy Research, November 2017, DOI: 10.1002/ptr.5958 11. Khalid El Bairi , Kanwal Tariq , Imane Himri , Abdeslam Jaafari, Wiam Smaili, Abdul Hafeez Kandhro, Adel Gouri, Bouchra Ghazi. Decoding Colorectal Cancer Epigenomics. Cancer Genetics. 220 (2018) 49–76 12. Lamyae El Khalkhi, Mounir Tilaoui, Abdeslam Jaafari, Hassan Ait Mouse, Abdelmajid Zyad. "Studies on the Dual Cytotoxicity and Antioxidant Properties of Berberis vulgaris Extracts and Its Main Constituent Berberine," Advances in Pharmacological Sciences, vol. 2018, Article ID 3018498, 11 pages, 2018 13. N. Bouchmaa, M. Tilaoui, Y. Boukharsa, A. Jaafari, H. Ait Mouse, My Ali Oukerrou, J. taoufik, M. Ansar and A. Zyad. In vitro antitumor activity of newly synthetized Pyridazun-3(2H)-onederivatives via apoptosis induction. Pharm. Chem. Journal. Vol. 51 ; N 10, January 2018. P : 893 14. CHAPTER IN BOOK « CYTOTOXICITY » A. Zyad ; I. Leouifoudi ; M. Tilaoui ; H. Ait Mouse ; M. Kouchani and A. Jaafari. Natural products as cytotoxic agents in chemotherapy against cancer. IntechOpen 72744, 2018, Chapter 5, pp : 65-88