Domaine de Maîtrise :
Biopathologie et Recherche Biomédicale

Domaine d’intérêt :
Biopathologie et Recherche Biomédicale**

Les publications :
Laarabi FZ, Ratbi I, Elalaoui SC, Mezzouar L, Doubaj Y, Bouguenouch L, Ouldim K, Benjaafar N, Sefiani A. High frequency of the recurrent c.1310_1313delAAGA BRCA2 mutation in the North-East of Morocco and implication for hereditary breast-ovarian cancer prevention and control. BMC Res Notes. 2017 Jun 2;10(1):188. doi: 10.1186/s13104-017-2511-2. PubMed PMID: 28577564; PubMed Central PMCID: PMC5457611.

Smaili W, Doubaj Y, Laarabi FZ, Lyahyai J, Kerbout M, Mikdame M, Sefiani A. CALR gene mutational profile in myeloproliferative neoplasms with non-mutated JAK2 in Moroccan patients: A case series and germline in-frame deletion. Curr Res Transl Med. 2017 Jan - Mar;65(1):15-19. doi: 10.1016/j.retram.2016.08.002. Epub 2016 Nov 3. PubMed PMID: 28340692.

Jouali F, Laarabi FZ, Marchoudi N, Ratbi I, Elalaoui SC, Rhaissi H, Fekkak J, Sefiani A. First application of next-generation sequencing in Moroccan breast/ovarian cancer families and report of a novel frameshift mutation of the BRCA1 gene. Oncol Lett. 2016 Aug;12(2):1192-1196. Epub 2016 Jun 16. PubMed PMID: 27446417; PubMed Central PMCID: PMC4950805.

Guaoua S, Ratbi I, Lyahyai J, El Alaoui SC, Laarabi FZ, Sefiani A. Novel nonsense mutation of BRCA2 gene in a Moroccan man with familial breast cancer. Afr Health Sci. 2014 Jun;14(2):468-71. doi: 10.4314/ahs.v14i2.25. PubMed PMID: 25320599; PubMed Central PMCID: PMC4196389.

Laarabi FZ, Cherkaoui Jaouad I, Baert-Desurmont S, Ouldim K, Ibrahimi A, Kanouni N, Frebourg T, Sefiani A. The first mutations in the MYH gene reported in Moroccan colon cancer patients. Gene. 2012 Mar 15;496(1):55-8. doi: 10.1016/j.gene.2011.12.024. Epub 2012 Jan 10. PubMed PMID: 22266422.

Laarabi FZ, Jaouad IC, Ouldim K, Aboussair N, Jalil A, Gueddari BE, Benjaafar N, Sefiani A. Genetic testing and first presymptomatic diagnosis in Moroccan families at high risk for breast/ovarian cancer. Oncol Lett. 2011 Mar;2(2):389-393. Epub 2011 Jan 21. PubMed PMID: 22866093; PubMed Central PMCID: PMC3410606.

Laarabi FZ, Cherkaoui Jaouad I, Benazzouz A, Squalli D, Sefiani A. Prevalence of MYH-associated polyposis related to three recurrent mutations in Morocco. Ann Hum Biol. 2011 May;38(3):360-3. doi: 10.3109/03014460.2010.521520. Epub 2010 Oct 13. PubMed PMID: 20939750.